Title:
PHARMACEUTICAL COMPOSITION FOR CONTROLLED RELEASE OF METHYLPHENIDATE
Document Type and Number:
Japanese Patent JP2015083599
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for controlled release which can control release pattern of methylphenidate contained in a core material as desired, and can shield the bitter taste of methylphenidate for a fixed time even if being exposed to oral cavity.SOLUTION: Disclosed is a pharmaceutical composition for controlled release, comprising a core material containing methylphenidate, and a plurality of particles for controlled release, containing a polymer coating layer for controlled release, formed on the core material. The plurality of particles for controlled release is divided into two or more groups based on the average thickness of the polymer coating layer for controlled release. The particle groups are identical in terms of the composition of the polymer in the polymer coating layer, but are different in terms of the average thickness of the coated layer. The pharmaceutical composition for controlled release may control the release pattern of methylphenidate contained in the core material as desired, and can be used as an oral formulation in a variety of forms including quick dissolving tablets.
More Like This:
| JP4511691 | Matrix patch for percutaneous administration |
| JP2001514177 | [Title of Invention] A compound having neuronal activity |
| JP2008543851 | Emetic-encapsulated capsule |
Inventors:
PARK SANG YEOB
CHUNG HOJIN
PAI CHAUL MIN
CHUNG HOJIN
PAI CHAUL MIN
Application Number:
JP2014264905A
Publication Date:
April 30, 2015
Filing Date:
December 26, 2014
Export Citation:
Assignee:
SAMYANG BIOPHARMACEUTICALS
International Classes:
A61K31/4458; A61K9/10; A61K9/16; A61K9/20; A61K9/26; A61K9/48; A61K47/10; A61K47/14; A61K47/32; A61K47/34; A61K47/38; A61P25/00; A61P25/14
Domestic Patent References:
| JP2002516848A | 2002-06-11 | |||
| JP2003171277A | 2003-06-17 | |||
| JPH05339151A | 1993-12-21 | |||
| JP2003520223A | 2003-07-02 | |||
| JP2004501190A | 2004-01-15 | |||
| JP2002532426A | 2002-10-02 | |||
| JP2008501741A | 2008-01-24 | |||
| JP2007520421A | 2007-07-26 | |||
| JP2005532387A | 2005-10-27 | |||
| JPH09500866A | 1997-01-28 | |||
| JPH08506802A | 1996-07-23 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda