Title:
薬物ののみ易さを改善するための医薬組成物及びその調製方法
Document Type and Number:
Japanese Patent JP4629730
Kind Code:
B2
Abstract:
The present invention discloses compositions, comprising a lipid-polymer matrix to mask the bitter or unpleasant taste of the medicament. The lipid or a blend of lipids, are used in combination with the pH dependent polymer where the said polymer is acid soluble or swellable. The process for the preparation of taste masked pharmaceutical compositions of the bitter drugs comprising the said lipid-polymer compositions are disclosed. The concomitant use of the acid soluble polymer, which remains collapsed at the pH of saliva, inhibits the release of drug at that pH and hence they further help in bitterness inhibition. The said compositions deliver substantial amount of the bitter drug immediately at the gastric pH with improved palatability.
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Inventors:
Men George, Anupa Ramesh
Kulkarni, Mohan Gopar Krishna
Kulkarni, Mohan Gopar Krishna
Application Number:
JP2007522124A
Publication Date:
February 09, 2011
Filing Date:
December 10, 2004
Export Citation:
Assignee:
Council of Scientific and Industrial Research
Men George, Anupa Ramesh
Kulkarni, Mohan Gopar Krishna
Men George, Anupa Ramesh
Kulkarni, Mohan Gopar Krishna
International Classes:
A61K47/32; A61K9/10; A61K9/107; A61K9/14; A61K9/20; A61K31/496; A61K31/546; A61K47/10; A61K47/12; A61K47/14; A61K47/16; A61K47/44; A61P31/04
Domestic Patent References:
| JP58072516A | ||||
| JP5505628A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Ayako Kondo
Takashi Ishida
Fukumoto product
Tetsuji Koga
Ayako Kondo