Title:
神経細胞損傷を軽減するための医薬組成物
Document Type and Number:
Japanese Patent JP5060703
Kind Code:
B2
Abstract:
Methods of suppressing the activation of microglial cells in the Central Nervous System (CNS), methods of ameliorating or treating the neurological effects of cerebral ischemia or cerebral inflammation, and methods of combating specific diseases that affect the CNS by administering a compound that binds to microglial receptors and prevents or reduces microglial activation are described. Also described are methods of screening compounds for the ability to suppress or reduce microglial activation.
Inventors:
Raskowitz, Daniel, Tee.
Matthew, William, Dee.
Macmillan, michael
Matthew, William, Dee.
Macmillan, michael
Application Number:
JP2003530125A
Publication Date:
October 31, 2012
Filing Date:
September 23, 2002
Export Citation:
Assignee:
Cognossi, Inc.
International Classes:
A61K38/00; A61K45/00; A61B1/00; A61K31/13; A61K31/135; A61K31/19; A61K31/197; A61K31/198; A61K31/27; A61K31/4015; A61K31/4166; A61K31/428; A61K31/436; A61K31/515; A61K31/519; A61K31/52; A61K31/53; A61K31/55; A61K38/04; A61K38/10; A61K38/16; A61K38/17; A61K38/18; A61K38/19; A61K38/20; A61K38/21; A61K39/02; A61K39/12; A61K39/395; A61P21/02; A61P23/00; A61P25/04; A61P25/14; A61P25/16; A61P25/18; A61P25/30; A61P29/00; A61P31/00; A61P43/00; C07K14/47; C07K14/775; C12N5/00; C12N5/02; C12N7/00; C12N7/01; C12Q1/68; G01N33/50; G01N33/92; C07K7/08; A61B
Domestic Patent References:
| JP2000217579A |
Foreign References:
| WO1999016464A1 | ||||
| WO1999015159A1 | ||||
| WO1998007751A1 | ||||
| WO1998011127A1 |
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Toshifumi Onuki