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Title:
PHARMACEUTICAL COMPOSITIONS COMPRISING, AS ACTIVE INGREDIENT, MIRNA LOCATED IN DLK1-DIO3 CLUSTER OR VARIANT THEREOF FOR PREVENTING OR TREATING MUSCULAR DISEASE OR CACHEXIA
Document Type and Number:
Japanese Patent JP2022160638
Kind Code:
A
Abstract:
To provide pharmaceutical compositions for preventing or treating muscular disease or cachexia.SOLUTION: There is disclosed, a pharmaceutical compositions comprising as an active ingredient, a miRNA located in Dlk1-Dio3 cluster or a variant thereof for preventing or treating muscular disease or cachexia, where the miRNA is anyone selected from a group consisting of miRNA-668, miRNA-376c, miRNA-494, miRNA-541, miRNA-377, miRNA-1197, miRNA-495, miRNA-300, miRNA-409, miRNA-544a, miRNA-379, miRNA-543 and miRNA-337.SELECTED DRAWING: Figure 12c

Inventors:
Kwon Gison
Lee Kampyo
Shin Yojin
Lee Bora
Lee Sung Min
Application Number:
JP2022127314A
Publication Date:
October 19, 2022
Filing Date:
August 09, 2022
Export Citation:
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Assignee:
AVENTI INC.
International Classes:
A61K31/7105; A61K35/76; A61K35/761; A61K48/00; A61P9/00; A61P21/00; A61P21/02
Foreign References:
KR20160131938A2016-11-16
Attorney, Agent or Firm:
Yamato Kento
Yasushi Ochiai