Title:
医薬化合物
Document Type and Number:
Japanese Patent JP7099672
Kind Code:
B2
Abstract:
Novel tetrahydroisoquinoline and tetrahydrobenzazepine compounds of formula (I) capable of modulating the G-protein-coupled receptor GPR120, compositions comprising the compounds, and methods for their use for controlling insulin levels in vivo and for the treatment of conditions such as of diabetes, inflammation, obesity and metabolic diseases.
Inventors:
Brown, jane
Connolly, Stephen
Hansen, Stephen, Buoy., F.
Milne, Gavin
Simpukade, Bharat
Smythe, Don
Thomas, Gerald
Ulven, Tronde
Boulevard, Matthias
Rigby, Aaron
Connolly, Stephen
Hansen, Stephen, Buoy., F.
Milne, Gavin
Simpukade, Bharat
Smythe, Don
Thomas, Gerald
Ulven, Tronde
Boulevard, Matthias
Rigby, Aaron
Application Number:
JP2020501850A
Publication Date:
July 12, 2022
Filing Date:
March 26, 2018
Export Citation:
Assignee:
Caldan Therapeutics Limited
International Classes:
C07D223/16; A61K31/472; A61K31/4725; A61K31/506; A61K31/55; A61P1/14; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P15/00; A61P17/00; A61P25/00; A61P27/02; A61P35/00; A61P43/00; C07D217/04; C07D401/04; C07D405/04; C07D413/06
Domestic Patent References:
| JP2009525275A | ||||
| JP2008512375A |
Foreign References:
| WO2016105118A2 | ||||
| WO2008053446A2 | ||||
| WO2009147990A1 |
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazuho
Kato Kazuho
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