Title:
高い安定性を持つ薬理組成物
Document Type and Number:
Japanese Patent JP5242415
Kind Code:
B2
Abstract:
The present invention provides for a stabilized biodegradable polymeric composition useful as a controlled release delivery system for peptide agents. The compositions of the present invention comprise a) a beneficial salt of a luteinizing hormone releasing hormone (LHRH) analogue formed with a strong acid that minimizes or prevents the interaction/reaction between the LHRH and the polymer in an organic solution; b) a biodegradable polymer; c) a pharmaceutically acceptable organic solvent; and d) optionally one or more excipients. The present invention also relates to a method of manufacturing and a method of use thereof.
Inventors:
Lee You Hua
Chien benjamin
Chien benjamin
Application Number:
JP2008551315A
Publication Date:
July 24, 2013
Filing Date:
January 16, 2007
Export Citation:
Assignee:
Forsea Acer Pharmaceuticals, Inc.
International Classes:
A61K38/00; A61K38/04; A61K38/21; A61K38/28; A61K38/43; A61K47/02; A61K47/12; A61K47/20; A61K47/22; A61K47/34; A61K47/48
Domestic Patent References:
| JP11193300A | ||||
| JP5032559A | ||||
| JP2002528403A | ||||
| JP2001522814A | ||||
| JP4208228A |
Foreign References:
| US20050042294 |
Attorney, Agent or Firm:
Koichi Tsujii
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Kazuo Yamazaki
Satsuki Ichikawa
Sadao Kumakura
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Kazuo Yamazaki
Satsuki Ichikawa