Title:
フェニルおよびピリジニル誘導体
Document Type and Number:
Japanese Patent JP4070957
Kind Code:
B2
Abstract:
The present invention is a series of compounds formed from phenyl substituted pyridine or benzene derivatives and their pharmaceutically acceptable salts. These compounds have shown high affinity as antagonists to the NK-1 receptor.
Inventors:
Michelle Bose
Flounder, Gweed
Godel, Thierry
Hoffmann, Torsten
Funkeler, Walter
Schneider, Patrick
Staderer, Heinz
Flounder, Gweed
Godel, Thierry
Hoffmann, Torsten
Funkeler, Walter
Schneider, Patrick
Staderer, Heinz
Application Number:
JP2000600981A
Publication Date:
April 02, 2008
Filing Date:
February 15, 2000
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07C211/44; A61K31/167; C07D295/12; A61K31/44; A61K31/496; A61K31/5377; A61P1/00; A61P1/04; A61P9/00; A61P11/02; A61P17/02; A61P19/02; A61P25/00; A61P25/06; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/36; A61P27/14; A61P29/00; A61P37/08; A61P43/00; C07C211/54; C07C233/29; C07C233/33; C07C233/44; C07C317/14; C07C317/40; C07C323/41; C07D213/75; C07D213/79; C07D213/81; C07D295/135; C07D401/04
Domestic Patent References:
| JP62192358A | ||||
| JP60116491A |
Foreign References:
| WO1999006353A1 |
Other References:
Anales de quimica international edition,1996, Vol.92, NO.6,page 400-404.
Chinese journal of applied chemistry,1995, Vol.12, No.4,page 80-83.
Tetrahedron letters,1989, Vol.30, No.9,page 1135-1138.
Ukrainskii Khimicheskii zhurnal,1984, Vol.50, NO.1,page 71-75.
Tetrahedron,1981, Vol.37, No.24,page 4239-4244.
Bulletin de la societe chimique de France,1981, Vol.3-4,page 141-146.
Pharmazie,1980, Vol.35, No.5-6,page 256-263.
Bulletin of the chemical society of Japan,1976, Vol.49, No.5,page 1391-1394.
Journal of the chemical society, perkin transactions 1,1974, Vol.4,page 423-430.
Zhurnal obshchei khimii,1950, Vol.20,page 2158-2167.
Journal of the chemical society,abstracts, 1950,page 311-317.
Recueil des travaux chimiques des pays-bas et de la belgique,1948, Vol.67,page 489-511.
Ann.,1933, Vol.507,page 1-13.
Chinese journal of applied chemistry,1995, Vol.12, No.4,page 80-83.
Tetrahedron letters,1989, Vol.30, No.9,page 1135-1138.
Ukrainskii Khimicheskii zhurnal,1984, Vol.50, NO.1,page 71-75.
Tetrahedron,1981, Vol.37, No.24,page 4239-4244.
Bulletin de la societe chimique de France,1981, Vol.3-4,page 141-146.
Pharmazie,1980, Vol.35, No.5-6,page 256-263.
Bulletin of the chemical society of Japan,1976, Vol.49, No.5,page 1391-1394.
Journal of the chemical society, perkin transactions 1,1974, Vol.4,page 423-430.
Zhurnal obshchei khimii,1950, Vol.20,page 2158-2167.
Journal of the chemical society,abstracts, 1950,page 311-317.
Recueil des travaux chimiques des pays-bas et de la belgique,1948, Vol.67,page 489-511.
Ann.,1933, Vol.507,page 1-13.
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda