Title:
リン酸ジエステル−リン酸トリエステル共重合体およびその合成方法ならびに骨標的薬物輸送担体
Document Type and Number:
Japanese Patent JP6679067
Kind Code:
B2
Abstract:
To provide a compound capable of being used as a bone targeting drug transport carrier capable of relatively easily carrying various drugs and transporting the same to bone, and low in toxicity to living matter.SOLUTION: The phosphoric diester-phosphotriester copolymer contains (a) a unit of phosphoric diester or a salt thereof, and (b) a unit of phosphotriester having a pendant group containing an ethynylene group (-C≡C-). Such phosphoric diester-phosphotriester copolymer can be used as a bone targeting drug transport carrier.SELECTED DRAWING: Figure 5
Inventors:
Iwa Saki Yasuhiko
Shinotaka Otaka
Junji Yokota
Masashi Neo
Shinotaka Otaka
Junji Yokota
Masashi Neo
Application Number:
JP2017143922A
Publication Date:
April 15, 2020
Filing Date:
July 25, 2017
Export Citation:
Assignee:
Kansai University
Osaka Medical and Pharmaceutical University
Osaka Medical and Pharmaceutical University
International Classes:
C08G79/04; A61K47/34; A61L27/18
Domestic Patent References:
| JP2015131914A |
Foreign References:
| US20140193504 |
Other References:
Journal of Biomaterials Science, Polymer Edition,2012年 8月 8日,24, 7,882-895
Attorney, Agent or Firm:
Hiroharu Kitahara
Satoshi Yamauchi
Seiko Ito
Satoshi Yamauchi
Seiko Ito