Title:
亜鉛結合部分を有するホスホイノシチド３−キナーゼインヒビター
Document Type and Number:
Japanese Patent JP5762520
Kind Code:
B2
Abstract:
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
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Inventors:
Tsai, Zion
Chai, Hai Xiao
Rye, Chen-Chun
Jiang, Changkung
Chai, Hai Xiao
Rye, Chen-Chun
Jiang, Changkung
Application Number:
JP2013271719A
Publication Date:
August 12, 2015
Filing Date:
December 27, 2013
Export Citation:
Assignee:
Curis, Inc.
International Classes:
C07D495/04; A61K31/519; A61K31/5377; A61K31/5386; A61P35/00; A61P35/02; A61P43/00; C07D491/048
Domestic Patent References:
| JP2008517894A | ||||
| JP5452617B2 |
Foreign References:
| WO2008073785A1 | ||||
| WO2008070740A1 | ||||
| WO2007127175A1 | ||||
| WO2007127183A1 | ||||
| WO2008033747A1 | ||||
| WO2008033743A1 | ||||
| WO2008033744A1 | ||||
| WO2008033745A1 | ||||
| WO2008033746A1 | ||||
| WO2008033748A1 | ||||
| WO2008033749A1 | ||||
| WO2009052145A1 | ||||
| WO2001083456A1 |
Attorney, Agent or Firm:
Yoshinori Hosoda