Title:
PHOTOACOUSTIC IMAGING AGENT WHICH HAS LIPID PARTICLE CONTAINING SILICON NAPHTHALOCYANINE ANALOG
Document Type and Number:
Japanese Patent JP2015028001
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To solve a problem that a conventional liposome containing silicon naphthalocyanine should be encapsulated in condition where dyes are dispersing, to be used in photodynamic therapy; is low in dye-containing rate; and also is low in a photoacoustic signal.SOLUTION: According to a lipid particle containing silicon naphthalocyanine analog, wherein ratio A/B of absorption coefficient A in first absorption maximum and absorption coefficient B in second absorption maximum in 700 nm to 800 nm is 5.0 or less, it is possible that the dye-containing rate in the lipid particle is increased and thereby intensity of a photoacoustic signal is improved.
Inventors:
TOMATSU FUMIKO
FUKUI SHIGE
SASAKURI DAISUKE
KISHI MAYUKO
KATO KOICHI
YUASA SATOSHI
FUKUI SHIGE
SASAKURI DAISUKE
KISHI MAYUKO
KATO KOICHI
YUASA SATOSHI
Application Number:
JP2014128939A
Publication Date:
February 12, 2015
Filing Date:
June 24, 2014
Export Citation:
Assignee:
CANON KK
International Classes:
A61K49/00; A61K9/127; A61K47/24; A61K47/28; A61K47/34; C09B67/08; C09B67/20
Attorney, Agent or Firm:
Okabe 讓
Shin-ichi Usui
Takao Ochi
Seiichiro Takahashi
Hiroshi Yoshizawa
Masami Saito
Katsuhiko Kimura
Takafumi Tanaka
Shin-ichi Usui
Takao Ochi
Seiichiro Takahashi
Hiroshi Yoshizawa
Masami Saito
Katsuhiko Kimura
Takafumi Tanaka