光増感剤、タンパク質切断剤、タンパク質切断方法、糖分子切断剤、糖分子切断方法、及び光線力学的治療剤

Title:

光増感剤、タンパク質切断剤、タンパク質切断方法、糖分子切断剤、糖分子切断方法、及び光線力学的治療剤

Document Type and Number:

Japanese Patent JP5046029

Kind Code:

B2

Abstract:

[PROBLEMS] To provide a novel photosensitizer, methods of cleaving a protein and cleaving a sugar molecule with light irradiation, and a protein-cleaving agent and sugar molecule-cleaving agent for use in these methods. [MEANS FOR SOLVING PROBLEMS] A compound represented by the following general formula (I) or a salt thereof generates active oxygen upon light irradiation and functions to cleave a protein and sugar molecules. The compound or salt is hence useful in applications such as a photosensitizer, protein-cleaving agent, sugar molecule-cleaving agent, and photodynamic therapeutic agent. [Chemical formula 1] (I) (In the formula, R₁ to R₈ each is hydrogen or a hydroxylated substituent, provided that at least one of R₁ to R₈ is a hydroxylated substituent.)

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Inventors:

Kazuma Atsushi

Application Number:

JP2007507210A

Publication Date:

October 10, 2012

Filing Date:

March 10, 2006

Export Citation:

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Assignee:

Keio University

International Classes:

C09K3/00; A61K31/122; A61K31/704; A61P43/00; C07C46/00; C07C50/34; C07H15/18; C07K1/12; C09B1/00; A61P3/04; A61P3/10; A61P31/04; A61P31/12; A61P35/00

Domestic Patent References:

JP2004010565A

2004-01-15

Foreign References:

US20040116536A1	2004-06-17
WO2003089577A2	2003-10-30

Attorney, Agent or Firm:

Isshiki International Patent Service Corporation

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