Title:
肝臓Ｘ受容体モジュレーターとしてのピペラジン誘導体
Document Type and Number:
Japanese Patent JP6605583
Kind Code:
B2
Abstract:
Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.
Inventors:
Claremon, David A
Dawn, Chu Young Guo
Fan, e
Lefteris, Katerina
Rota, Stephen Dee
Shin, Suresh Bee
Tice, Colin M
Jao, Way
Juyoung, Yajun
Lehan
Dawn, Chu Young Guo
Fan, e
Lefteris, Katerina
Rota, Stephen Dee
Shin, Suresh Bee
Tice, Colin M
Jao, Way
Juyoung, Yajun
Lehan
Application Number:
JP2017506842A
Publication Date:
November 13, 2019
Filing Date:
August 04, 2015
Export Citation:
Assignee:
Vity Pharmaceuticals, LRC
International Classes:
A61K31/495; C07D241/04; A61K31/506; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P17/00; A61P17/02; A61P17/06; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07D401/04; C07D401/06; C07D403/04; C07D403/06; C07D407/06; C07D413/04; C07D413/14; C07D417/04; C07D417/14; C07D451/00
Domestic Patent References:
| JP2013525479A |
Foreign References:
| WO2014101113A1 | ||||
| WO2013138565A1 |
Attorney, Agent or Firm:
Shinjiro Ono
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Ichinomiya
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi
Ichinomiya