PIPERIDINE MCH ANTAGONIST AND APPLICATION OF THE SAME TO TREATMENT OF OBESITY

Title:

PIPERIDINE MCH ANTAGONIST AND APPLICATION OF THE SAME TO TREATMENT OF OBESITY

Document Type and Number:

Japanese Patent JP2007284451

Kind Code:

A

Abstract:

To provide an antagonist to melanine-concentrating hormone (MCH).

A compound expressed by structural formula (I), pharmaceutically permissible salts, esters or solvates of the same, a pharmaceutical composition containing the compound and application of the compound to treatments for eating disorders and diabetes are provided. The method for treating eating disorders and diabetes includes a process for administering an effective amount of the compound expressed by the structural formula (I) to mammals requiring the treatments for eating disorders (e.g., obesity and hyperphagia) and diabetes. Another aspect of affairs of the invention is the pharmaceutical composition for treatments for eating disorders and obesity containing the compound expressed by the structural formula (I) combined with a pharmaceutically acceptable carrier.

Inventors:

MCKITTRICK BRIAN A
SU JING
CLADER JOHN W
LI SHENGJIAN
GUO GUIHUA

Application Number:

JP2007195250A

Publication Date:

November 01, 2007

Filing Date:

July 26, 2007

Export Citation:

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Assignee:

SCHERING PLOUGH CORP

International Classes:

C07D211/30; A61K31/445; C07D211/34; A61K31/4525; A61K31/453; A61K31/454; A61K31/4709; A61K31/4965; A61K31/498; A61K31/517; A61P3/04; A61P3/10; A61P43/00; C07D401/06; C07D405/06; C07D413/06; C07D417/06; A61K31/4545

Attorney, Agent or Firm:

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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