Title:
ケモカイン受容体活性のピペリジニル-アルファ-アミノアミドモジュレーター
Document Type and Number:
Japanese Patent JP2006514618
Kind Code:
A
Abstract:
The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, W, X, Z, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
Inventors:
Yang, Lifou
Chiyo, Chiyan Yu
Chiyo, Chiyan Yu
Application Number:
JP2004550128A
Publication Date:
May 11, 2006
Filing Date:
October 24, 2003
Export Citation:
Assignee:
MERCK & COMPANY INCOPORATED
International Classes:
C07D205/04; A61K31/4025; A61K31/4035; A61K31/438; A61K31/4439; A61K31/445; A61K31/4453; A61K31/4523; A61K31/4525; A61K31/4535; A61K31/454; A61K31/4545; A61K31/472; A61P19/02; A61P29/00; A61P37/02; A61P43/00; C07D207/04; C07D207/22; C07D209/44; C07D211/08; C07D211/60; C07D215/48; C07D217/26; C07D223/04; C07D295/12; C07D295/13; C07D307/52; C07D307/54; C07D333/10; C07D333/24; C07D401/06; C07D401/12; C07D403/06; C07D491/052; A61K31/165
Domestic Patent References:
JP2000502702A | 2000-03-07 | |||
JPS63146871A | 1988-06-18 | |||
JP2000510164A | 2000-08-08 | |||
JP2006511500A | 2006-04-06 |
Foreign References:
WO2002044183A2 | 2002-06-06 | |||
WO2001010799A1 | 2001-02-15 | |||
US2948736A | 1960-08-09 | |||
WO1999000362A1 | 1999-01-07 | |||
DE2128941A1 | 1971-12-16 | |||
WO2003039451A2 | 2003-05-15 | |||
WO2002100832A1 | 2002-12-19 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura
Makoto Ono
Katsuma Osaki
Mitsuaki Tsubokura