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Title:
ピタバスタチンカルシウムおよびその調製方法
Document Type and Number:
Japanese Patent JP2013536219
Kind Code:
A
Abstract:
The invention provides the process for the preparation of pitavastatin and its pharmaceutically acceptable salts thereof. In particular, the invention provides a process for the preparation of stable pitavastatin calcium in crystalline form having water content less than 5% wt/wt. The present invention also provides stable crystalline form of pitavastatin calcium substantially free from crystal Form-A and use thereof for pharmaceutical compositions.

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Inventors:
Shri Prakash Dar Divedi
Dimant Jasbhai Patel
Alpes Pravin Chandra Shah
Brigi Kera
Application Number:
JP2013525424A
Publication Date:
September 19, 2013
Filing Date:
August 24, 2011
Export Citation:
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Assignee:
Cadilla Healthcare Limited
International Classes:
C07D215/14; A61K31/47; A61P3/06; A61P43/00
Domestic Patent References:
JP2007516952A2007-06-28
Foreign References:
US0009018A1852-06-15
US0004024A1845-05-01
CN101195603A2008-06-11
WO2010077062A22010-07-08
Other References:
JPN5013009910; ＭＡＮＮＥ　ＳＡＴＹＡＮＡＲＡＹＡＮＡ　ＲＥＤＤＹ: 'ＡＮ　ＩＭＰＲＯＶＥＤ　ＩＮＤＵＳＴＲＩＡＬ　ＰＲＯＣＥＳＳ　ＦＯＲ　ＳＹＮＴＨＥＳＩＳ　ＯＦ　ＨＭＧ-ＣＯＡ　ＲＥＤＵＣＴＡＳＥ　ＩＮＨＩＢＩＴＯＲ　ＰＩＴＡＶＡＳＴＡＴＩＮ' ＯＲＩＥＮＴＡＬ　ＪＯＵＲＮＡＬ　ＯＦ　ＣＨＥＭＩＳＴＲＹ Ｖ２３　Ｎ２, 20070101, Ｐ５５９-５６４
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro



 
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