Title:
PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS
Document Type and Number:
Japanese Patent JP2022068205
Kind Code:
A
Abstract:
To provide a method of characterizing candidate agents.SOLUTION: The method includes steps of (a) providing a library of candidate agents attached to nucleic acid tags; (b) contacting the library with a solid support to attach the candidate agents to the solid support, so that an array of candidate agents is formed; (c) contacting the array with a screening agent, where one or more candidate agents in the array react with the screening agent; (d) detecting the array to determine that at least one candidate agent in the array reacts with the screening agent; (e) sequencing the nucleic acid tag to determine the tag sequences attached to candidate agents in the array; and (f) identifying the at least one candidate agent in the array that reacts with the screening agent based on the tag sequence that is attached to the at least one candidate agent.SELECTED DRAWING: Figure 1-1
Inventors:
MOLLY HE
MICHAEL PREVITE
MISHA GOLYNSKIY
MATTHEW WILLIAM KELLINGER
SERGIO PEISAJOVICH
JONATHAN MARK BOUTELL
MICHAEL PREVITE
MISHA GOLYNSKIY
MATTHEW WILLIAM KELLINGER
SERGIO PEISAJOVICH
JONATHAN MARK BOUTELL
Application Number:
JP2022014932A
Publication Date:
May 09, 2022
Filing Date:
February 02, 2022
Export Citation:
Assignee:
ILLUMINA INC
International Classes:
C12Q1/6837; C12Q1/02; C12Q1/25; C12Q1/34; C12Q1/37; C12Q1/42; C12Q1/48; G01N33/15; G01N33/50
Domestic Patent References:
| JP2011516072A | 2011-05-26 |
Foreign References:
| WO2013096777A2 | 2013-06-27 |
Attorney, Agent or Firm:
Kenji Sugimura
Mitsutsugu Sugimura
Takao Inoue
Mitsutsugu Sugimura
Takao Inoue