Title:
ポリマー、生体内分解性材料および用途
Document Type and Number:
Japanese Patent JP4524923
Kind Code:
B2
Abstract:
A polymer having a satisfactory balance between in vivo degradability and satisfactory mechanical properties, which is an A<1>BA<2> type polymer comprising a segment A<1> and a segment A<2> each having a modified amino acid and a segment B consisting of polyethylene glycol with a number-average molecular weight of 8000 or higher bonded at one end to the segment A<1> and at the other end to the segment A<2>, and has a number-average molecular weight of 10000 to 600000; an in vivo degradable material which comprises the polymer; and a film for preventing tissue adhesion, an artificial dura mater, a suture, an implant preparation, or a sustained-release drug base each comprising the degradable material.
Inventors:
Atsuhiko Ogura
Hiroshi Iwasaki
Shinji Tanaka
Hiroshi Iwasaki
Shinji Tanaka
Application Number:
JP2000619989A
Publication Date:
August 18, 2010
Filing Date:
May 18, 2000
Export Citation:
Assignee:
NOF CORPORATION
International Classes:
C08G69/40; A61L17/00; A61L17/10; A61L27/00; A61L27/14; A61L27/16; A61L31/04; C08G65/333; C08G69/10; C08G69/44; C08G81/00; C08L71/02
Domestic Patent References:
| JPH0853548A | 1996-02-27 | |||
| JPS63132939A | 1988-06-04 |
Foreign References:
| WO1992000748A1 | 1992-01-23 | |||
| WO1992016555A1 | 1992-10-01 | |||
| EP0397307A2 | 1990-11-14 |
Other References:
CHO, CHONG SU; NAGATA, RYOHEI; YAGAWA, AKIO; TAKAHASHI, SUMIKA; KUNOU,MEGUMI; AKAIKE, TOSHIHIRO: "Monolayers of poly(γ-benzyl L-glutamate)/polyether block copolymers on the air/water interface", JOURNAL OF POLYMER SCIENCE, PART C: POLYMER LETTERS, vol. 28(3), JPN6009058437, 1990, pages 89 - 93, ISSN: 0001610767
OH, IN JOON; OH, JHIN YEE; CHO, CHONG SU; LEE, KANG CHOON: "Biodegradability of poly(γ-benzyl L-glutamate)/poly(ethylene oxide)/poly(γ-benzyl L-glutamate) blo", ARCHIVES OF PHARMACAL RESEARCH, vol. 18(1), JPN6009058440, 1995, pages 8 - 11, ISSN: 0001610768
OH, IN JOON; OH, JHIN YEE; CHO, CHONG SU; LEE, KANG CHOON: "Biodegradability of poly(γ-benzyl L-glutamate)/poly(ethylene oxide)/poly(γ-benzyl L-glutamate) blo", ARCHIVES OF PHARMACAL RESEARCH, vol. 18(1), JPN6009058440, 1995, pages 8 - 11, ISSN: 0001610768
Attorney, Agent or Firm:
Hajime Sakai
Masahiro Kurai
Masahiro Kurai