Title:
POLYMORPHS AND AMORPHOUS FORMS OF 5-AMINO-1-[2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]-4-[(TRIFLUOROMETHYL)SULFINYL]-1H-PYRAZOLE-3-CARBONITRILE
Document Type and Number:
Japanese Patent JP2013144678
Kind Code:
A
Abstract:
To provide efficient methods for the preparation and purification of fipronil, which are simple and can be used on a large scale for industrial manufacture, and which produce highly pure product that can be safely utilized.
The present invention relates to novel crystalline polymorphs, solvate pseudomorphs and amorphous form of 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile (fipronil). The present invention also provides methods for preparing the novel polymorphs, pseudomorphs and amorphous form, as well as insecticidal or pesticidal compositions comprising the same, and methods of use thereof as pesticidal agents.
Inventors:
ZAMIR SHARONA
Application Number:
JP2013010305A
Publication Date:
July 25, 2013
Filing Date:
January 23, 2013
Export Citation:
Assignee:
MAKHTESHIM CHEM WORKS LTD
International Classes:
A01N43/56; C07D231/44; A01P7/02; A01P7/04; A61K31/415; A61P33/00
Domestic Patent References:
| JPH07278106A | 1995-10-24 | |||
| JP2003512456A | 2003-04-02 | |||
| JP2005112738A | 2005-04-28 | |||
| JP2003519698A | 2003-06-24 |
Other References:
LIN, SUYONG ET AL., NONGYAO, vol. Vol.41(3), JPN6012038442, 2002, pages 19, ISSN: 0002814427
Attorney, Agent or Firm:
Katsuma Osaki
Chihiro Watanabe
Chihiro Watanabe