Title:
PREPARATION OF 3-MERCAPTOPROPIONITRILE AND 3-MERCAPTOPROPIONIC ACID
Document Type and Number:
Japanese Patent JP3836518
Kind Code:
B2
Abstract:
PURPOSE: To provide a method for preparing 3-mercaptopropionic acid by which the 3-mercaptopropionic acid can more efficiently be produced at a lower reaction temperature in a time shorter than those of a conventional method.
CONSTITUTION: Acrylonitrile in a molar excessive amount is reacted with an alkaline hydrosulfide (preferably sodium hydrosulfide), preferably in amounts of 2 mol former and 1 mol latter at a temperature of 35-45°C, to produce thiodipropionitrile in a nearly quantitative yield, which is then reacted with the alkaline hydrosulfide in the presence of a base, preferably potassium hydroxide, sodium hydroxide or triethanolamine to provide 3-mercaptopropionitrile. The resultant 3-mercaptopropionitrile is further acidified with a strong acid such as hydrochloric acid or sulfuric acid to afford 3-mercaptopropionic acid. The 3-mercaptopropionitrile and 3-mercaptopropionic acid without containing the dithiodipropionitrile and dithiopropionic acid as impurities can be produced in high yield by the method.
Inventors:
Richard P. Woodbury
F. David Wood
F. David Wood
Application Number:
JP8822895A
Publication Date:
October 25, 2006
Filing Date:
April 13, 1995
Export Citation:
Assignee:
Hampshire Chemical Corp.
International Classes:
C07C323/52; C07C319/06; C07C319/12; C07C323/60; (IPC1-7): C07C323/52; C07C319/12
Domestic Patent References:
| JP4183464A | ||||
| JP4145063A | ||||
| JP3074362A | ||||
| JP2121962A | ||||
| JP61151163A | ||||
| JP58198460A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Atsushi Ebiya
Masaya Nishiyama
Takashi Ishida
Tetsuji Koga
Atsushi Ebiya
Masaya Nishiyama