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Title:
PREPARATION AND COMPOSITION OF INTER-ALPHA INHIBITOR PROTEINS FROM BLOOD
Document Type and Number:
Japanese Patent JP2015155434
Kind Code:
A
Abstract:
【課題】血液からインター−アルファ−阻害タンパク質（ＩαＩｐ）を精製する方法及びその組成物の提供。【解決手段】クロマトグラフィー担体に結合したインター−アルファ−阻害タンパク質（ＩαＩｐタンパク質）を、２．０〜４．０のｐＨを有する洗浄緩衝液に曝露する洗浄工程を含有してなり、該洗浄工程が担体からＩαＩｐタンパク質の１５％以下の減少をもたらす、ＩαＩｐタンパク質を精製する方法で製造された、精製されたＩαＩｐタンパク質。【選択図】なし

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Inventors:
LIM YOW-PIN
EDWARD S SIRYA
PETER BRNE
Application Number:
JP2015080358A
Publication Date:
August 27, 2015
Filing Date:
April 09, 2015
Export Citation:
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Assignee:
PROTHERA BIOLOG INC
International Classes:
C07K14/81; A61K38/00; A61P15/06; A61P17/02; A61P19/02; A61P29/00; A61P31/04; A61P35/00; A61P35/04
Domestic Patent References:
JP2007515397A2007-06-14
JP2006520390A2006-09-07
JP2003292459A2003-10-15
JP2005531521A2005-10-20
JP2003040775A2003-02-13
Other References:
JOURNAL OF CHROMATOGRAPHY A, vol. 1065, JPN6016012250, 2005, pages 39 - 43, ISSN: 0003739083
Attorney, Agent or Firm:
Norio Saeki



 
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