PURPOSE: To industrially advantageously obtain ortho-amides by the reaction of alkoxymethylene iminium salts or formamidinium salts with alcoholates having a highly activated state.
CONSTITUTION: Salts expressed by formula I are allowed to react with alcoholates expressed by M1OR1 (M1 is alkali metal or alkaline earth metal; R1 is alkyl, alkenyl, alkoxyalkyl, alkoxyalkenyl, cycloalkyl, alkylene-OM1 or aralkyl) of a highly activated state to obtain ortho-amides expressed by formula II. In formula I, R2, R3 are each alkyl, alkenyl, alkoxyalkyl, alkoxyalkenyl, cycloalkyl, aryl, aralkyl, a 5 to 7-member satd. or unsatd. heteroring having one or two heteroatoms (N, O, S); R4 is OR5, NR5R6 (R5, R6 are each R2 or R3); X- is alkylsulfate anion, arylsulfonic acid anion, chloride anion, hexafluorophosphoric acid anion, etc.
HERUMUUTO KURAUSU
GERUHARUTO MARUTSUORUFU
NIKORAUSU MIYURAA
