Title:
システイン/グリシンリッチペプチドを含む調製物およびその使用
Document Type and Number:
Japanese Patent JP4348402
Kind Code:
B2
Abstract:
Described is a method for the preparation of a mixture of peptides having a cysteine content between 7-20 w/w % from a protein source, comprising cysteine containing proteins, comprising the steps of: a) cleaving the proteins of the protein source into peptides; b) digesting the peptides obtained in step a) by an exopeptidase, the action of which is at least attenuated at the position of a cysteine in the peptide, therewith forming digested peptides having a terminal cysteine; c) purifying the digested peptides, and the use of the preparation as active component in a medicament, especially for the treatment of conditions mediated by oxidative damage and for the elevation of cellular glutathion levels in the human or animal body.
Inventors:
Leon Franciscus Murray
Lamb Nimagudda
Johannes Wilhelms Leonardus Boumans
Lamb Nimagudda
Johannes Wilhelms Leonardus Boumans
Application Number:
JP2009037803A
Publication Date:
October 21, 2009
Filing Date:
February 20, 2009
Export Citation:
Assignee:
Campina B.V.
International Classes:
C07K2/00; A23J3/34; A23L2/66; A23L33/18; A23L33/19; A61K38/00; A61P9/10; A61P27/12; A61P35/00; A61P39/06; A61P43/00; C07K4/00; C12P21/06
Domestic Patent References:
| JP5287000A | ||||
| JP9009880A | ||||
| JP7115913A | ||||
| JP7264992A | ||||
| JP8112063A | ||||
| JP9028306A | ||||
| JP2000287698A |
Foreign References:
| WO2000030474A1 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Mizuhara Masahiro
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Nishino Mitsuru
Mizuhara Masahiro