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Title:
ニューレグリン調合剤の処方
Document Type and Number:
Japanese Patent JP7100083
Kind Code:
B2
Abstract:
The invention relates to a pharmaceutical formulation of neuregulin (NRG) comprising: (a) a NRG polypeptide, and (b) a buffering agent, wherein said formulation has a pH in a range from about 2.0 to about 5.7. The invention further relates to a lyophilized pharmaceutical formulation of NRG, prepared by lyophilization of the pharmaceutical formulation of the invention, wherein an excipient is added into the pharmaceutical formulation prior to the lyophilization.

Inventors:
Ming Dong Zuhou
Application Number:
JP2020082456A
Publication Date:
July 12, 2022
Filing Date:
May 08, 2020
Export Citation:
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Assignee:
Zensan (Shanghai) Science and Technology, Cio., RTD.
International Classes:
A61K38/19; A61K9/08; A61K9/19; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/18; A61K47/22; A61K47/26; A61K47/42; A61P9/04
Domestic Patent References:
JP6703483B2
JP2009522209A
Other References:
Current Opinion in Neurobiology,2001年,Vol.11,p.287-296
Attorney, Agent or Firm:
Toru Ishikawa