To provide a pressure sensor wire assembly which outputs an accurate pressure value, is easy to operate, and is manufactured at a low cost.

The assembly comprises a pressure sensor element for generating pressure sensor signal corresponding to pressure within the body of a patient and a pressure sensor wire having the pressure sensor element at its distal portion, and adapted to be inserted into the body in order to position the sensor element within the body. In addition, the assembly is provided with a sensor signal adapting circuitry being an integrated part of the assembly, wherein the pressure sensor signal is applied to the adapting circuitry to automatically generate an output pressure signal relative to the signal in a format suitable for an external physiology monitor. The assembly further comprises an external pressure sensor to measure pressure in the outside of the body of the patient and uniquely generate the pressure outside the patient's body, the external pressure values being applied to a pressure compensation means to generate a compensation value reflecting variation of external pressure during the measurement, wherein the output pressure signal is compensated by correcting values before it is applied to the external physiology monitor.