To prepare a new preventing and therapeutic agent for inflammatory intestinal diseases capable of safely and effectively acting on a lesion in a small dose and preventing and treating the inflammatory intestinal diseases by using a water-soluble specific chromanol glycoside as an active ingredient.
This new preventing and therapeutic agent for inflammatory intestinal diseases is prepared by formulating a chromanol glycoside represented by the formula [R1 to R4 are each H or a lower alkyl; R5 is H, a lower alkyl or a lower acyl; X is a monosaccharide residue or an oligosaccharude residue in which H of hydroxyl group in a saccharide residue may be substituted with a lower alkyl group or a lower acyl group; (n) is an integer of 0-6; (m) is an integer of 1-6] [e.g. 2-(α-D-lucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol] as an active ingredient into an aqueous pharmaceutical preparation, etc. The resultant preparation is capable of safely and effectively acting on lesions in a small dose and preventing and treating inflammatory intestinal diseases such as ulcerative colitis or Crohn's disease.
YOSHIDA NORIMASA
MURASE HIRONORI
YOSHIKAWA TOSHIICHI
| JPH07118287A | 1995-05-09 | |||
| JPH08269080A | 1996-10-15 | |||
| JPH0725867A | 1995-01-27 | |||
| JPH07112980A | 1995-05-02 |
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