PREVENTING AND THERAPEUTIC AGENT FOR OSTEOPOROSIS

Title:

PREVENTING AND THERAPEUTIC AGENT FOR OSTEOPOROSIS

Document Type and Number:

Japanese Patent JPH08268888

Kind Code:

A

Abstract:

PURPOSE: To obtain the subject new agent containing a specific compound as an active ingredient, having an excellent suppressing effect on bone resorption.

CONSTITUTION: This preventing and therapeutic agent for osteoporosis contains the compound of the formula UCS15A as an active ingredient. UCS15A is preferably obtained by culturing an actinomyces belonging to the genus Streptomyces, and then isolating and purifying. The daily dosage of the UCS15A is usually 0.1-2mg/kg for an adult. Specifically, e.g. the objective medicine is obtained as tablets e.g. by blending 100g UCS15A, 40g lactose, 18g corn starch and 10g CMC calcium, adding 10% aqueous solution of hydroxypropylcellulose and kneading, then granulating the kneaded liquid, preparing the granules by adding magnesium stearate, and finally tableting the obtained granules for tableting.

Inventors:

TAMAOKI TATSUYA
SUGAWARA KATSURA
HAMADA MASAKO
NAKANO HIROFUMI
MIZUKAMI TAMIO
YAMASHITA NOBUNORI
KOSAKA NOBUO
SUGIYAMA TOMOYOSHI

Application Number:

JP6972695A

Publication Date:

October 15, 1996

Filing Date:

March 28, 1995

Export Citation:

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Assignee:

KYOWA HAKKO KOGYO KK

International Classes:

C07D493/10; A61K31/35; A61P3/02; A61P3/14; A61P19/10; A61P43/00; (IPC1-7): A61K31/35; A61K31/35

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