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Title:
PREVENTION AND TREATMENT OF SYNUCLEINOPATHY
Document Type and Number:
Japanese Patent JP2012041338
Kind Code:
A
Abstract:

To provide an improved agent and a method for treatment of a disease associated with synucleinopathy, including a Lewy body of alpha-synuclein in the brain of a patient.

The method includes administering the agent that induces a beneficial immunogenic response against the Lewy body. The method is particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.


Inventors:
SCHENK DALE B
MASLIAH ELIEZER
Application Number:
JP2011162428A
Publication Date:
March 01, 2012
Filing Date:
July 25, 2011
Export Citation:
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Assignee:
ELAN PHARM INC
UNIV CALIFORNIA
International Classes:
A61K39/00; A61B1/00; A61K38/00; A61K38/17; A61K39/395; A61K45/06; A61K47/48; A61K48/00; A61K51/10; A61P25/16; A61P25/28; A61P43/00; C12Q1/00; C12Q1/02; G01N33/15; G01N33/50; G01N33/53; G01N33/577; A01K67/027; C07K14/47; C07K16/18; C12N15/09; A61B
Foreign References:
WO2000072876A22000-12-07
Other References:
JPN6009067002; WAKABAYASHI,K. et al, NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's di
JPN6012042349; Neuroscience 2002 Abstract , 20020827
Attorney, Agent or Firm:
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Takumi Terachi