Title:
Ｓ−ケタミンの（Ｓ）−ＣＳＡ塩、Ｓ−ケタミンの（Ｒ）−ＣＳＡ塩、及びＳ−ケタミンの調製プロセス
Document Type and Number:
Japanese Patent JP6882990
Kind Code:
B2
Abstract:
The present invention is directed to processes for the preparation of esketamine. The present invention is further directed to processes for the resolution of S-ketamine from a racemic or enantiomerically enriched mixture of ketamine. The present invention is further directed to an (S)-CSA salt of S-ketamine, more particularly a monohydrate form of the (S)-CSA salt of S-ketamine; and to an (R)-CSA salt of R-ketamine.
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Inventors:
Shen, Chen Yi
Flow gel, Oliver
Justus, michael
Maurer, Adrian
Curl reuters
Strittmatter, Tobias
Wedel, Tobias
Flow gel, Oliver
Justus, michael
Maurer, Adrian
Curl reuters
Strittmatter, Tobias
Wedel, Tobias
Application Number:
JP2017558956A
Publication Date:
June 02, 2021
Filing Date:
May 13, 2016
Export Citation:
Assignee:
Janssen Pharmaceuticals N.B.
International Classes:
C07C225/20; A61K31/135; A61P9/12; A61P11/08; A61P25/00; A61P25/04; A61P25/24; C07C221/00; C07C309/19
Domestic Patent References:
| JP49048542B1 | ||||
| JP2000510135A | ||||
| JP2015078181A | ||||
| JP63192753A | ||||
| JP51095036A | ||||
| JP63014771A | ||||
| JP2009534349A |
Foreign References:
| US20030212143 |
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Junko Kobayashi
Norio Omori
Uetake Yukiko
Yasuhito Suzuki
Eiji Katayama
Junko Kobayashi
Norio Omori
Uetake Yukiko
Yasuhito Suzuki