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Title:
PROCESS FOR PREPARING INDANE DERIVATIVES
Document Type and Number:
Japanese Patent JPS51125368
Kind Code:
A
Abstract:
Indane of formula (I) (where X is H or halogen; R1 and R2 are each 1-5C-alkyl or 3-7C-cycloalkyl, and one of R1 and R2 can be H; R3 is H or 1-5C-alkyl; Y is CH2OH, COOR4 or (CH2)n NR5R6; R4 is H or M 1/v; M is a metal and v is its valence; n is 1-5; R5 and R6 are each H 1-5C-alkyl, 3-7C-cycloalkyl, aryl or aralkyl, or NR5R4 is an opt. substd. 5 to 7-membered N-contg. heterocyclic ring opt. contg. a second heteroatom) are used as antiinflammatory and analgesic agents esp. antirheumatic agents of LD50 (rat) 250 mg/kg (orally).

Inventors:
JIYAN MARIE TEERON
Application Number:
JP1677775A
Publication Date:
November 01, 1976
Filing Date:
February 07, 1975
Export Citation:
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Assignee:
HEXACHIMIE
International Classes:
A61K31/045; A61K31/21; A61K31/215; A61K31/22; A61P25/04; A61P29/00; C07C17/32; C07C27/00; A61K31/19; C07C29/136; C07C29/147; C07C33/34; C07C33/50; C07C45/46; C07C49/792; C07C51/00; C07C51/08; C07C57/50; C07C57/62; C07C67/00; C07C213/00; C07C219/10; C07D295/088; C07D295/194; (IPC1-7): A61K31/19; A61K31/22; A61K31/445; A61K31/535; C07C31/13; C07C61/38; C07C101/18; C07D295/00