Title:
PROCESSES AND INTERMEDIATES FOR PREPARING MCL1 INHIBITORS
Document Type and Number:
Japanese Patent JP2023126636
Kind Code:
A
Abstract:
To provide methods for treating diseases.SOLUTION: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates. The present disclosure relates to methods and intermediates for the synthesis of certain compounds which inhibit MCL1, for use in the treatment of cancers. The present disclosure provides methods for making compounds according to Formula (A), as shown above. In some embodiments, the present disclosure provides compounds according to Formula (I).SELECTED DRAWING: None
Inventors:
KATRIEN BRAK
KAE M BULLOCK
GREG CIZIO
KATHY DAO
DARRYL D DIXON
JOSHUA R DUNETZ
LUKE D HUMPHREYS
VALERIE HUYNH
MICHAEL A ISCHAY
TREVOR C JOHNSON
JEFFREY E MERIT
CHRISTOPHER S REGENS
ERIC A STANDLEY
DIETRICH P STEINHUEBEL
JUSTIN Y SU
WU TAO
MARSHALL D YOUNG
KAE M BULLOCK
GREG CIZIO
KATHY DAO
DARRYL D DIXON
JOSHUA R DUNETZ
LUKE D HUMPHREYS
VALERIE HUYNH
MICHAEL A ISCHAY
TREVOR C JOHNSON
JEFFREY E MERIT
CHRISTOPHER S REGENS
ERIC A STANDLEY
DIETRICH P STEINHUEBEL
JUSTIN Y SU
WU TAO
MARSHALL D YOUNG
Application Number:
JP2023118560A
Publication Date:
September 07, 2023
Filing Date:
July 20, 2023
Export Citation:
Assignee:
GILEAD SCIENCES INC
International Classes:
C07C43/178; C07C69/157; C07C311/11; C07C381/10; C07D267/16; C07D317/20; C07D317/22; C07D317/24; C07D319/08; C07D515/08; C07F7/18
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Natsuki Morishita
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