PROCESSES FOR PRODUCTION OF (+)-"NAL" MORPHINAN COMPOUNDS

Title:

PROCESSES FOR PRODUCTION OF (+)-"NAL" MORPHINAN COMPOUNDS

Document Type and Number:

Japanese Patent JP2014055179

Kind Code:

A

Abstract:

To provide processes and intermediate compounds useful for production of (+)-opiates.

The invention generally provides processes and intermediate compounds useful for production of (+) nal morphinan compounds. In particular, the process encompasses synthetic routes for production of (+) nal morphinan compounds or derivatives of (+) nal morphinan compounds from (+)-morphinan substrates such as (+)-hydrocodone, (+)-norhydrocodone or derivatives of either compound.

More Like This:

WO/2002/081477	7-SUBSTITUTED MORPHINANE DERIVATIVES AND MEDICINAL USE THEREOF
JP2012518651	(+)-Morphinanium N-oxides and their production methods
WO/2011/005452	METHOD FOR THE ENRICHMENT OF BUPRENORPHINE USING CHROMATOGRAPHIC TECHNIQUES

Inventors:

WANG PETER X
TAO JIANG
CANTRELL GARY L
BERBERICH DAVID W
TRAWICK BOBBY N
LIAO SUBO

Application Number:

JP2013261253A

Publication Date:

March 27, 2014

Filing Date:

December 18, 2013

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MALLINCKRODT LLC

International Classes:

C07D489/02; C07D489/08; C07B53/00

Attorney, Agent or Firm:

Takeshi Oshio

Previous Patent: INHIBITION OF INFLAMMATION USING α7 RECEPTOR-BINDING CHOLINERGIC AGONIST

Next Patent: EYE DROP FOR SILICONE HYDROGEL CONTACT LENS