Title:
PRODUCTION OF 1-(4-HYDROXYPHENYL)-2-HYDROXY-1-ETHANONES
Document Type and Number:
Japanese Patent JP3176967
Kind Code:
B2
Abstract:
PURPOSE: To simply and inexpensively obtain the subject compound useful as an intermediate for medicines, agricultural chemicals, etc., in one step by condensing a phenol to glyoxal in the presence of a basic substance.
CONSTITUTION: A phenol (preferably phenol) is subjected to condensation reaction with glyoxal in the presence of a basic substance such as NaOH or KOH, preferably at 25-65°C, normally for 0.5-8hr to provide the objective compound. The phenol and glyoxal are preferably added in a ratio of (10/1) to (1/1) and the ratio of the addition amount of the basic substance to glyoxal is preferably (1/1) to (0.1/1). Furthermore, the reaction is carried out under an inert gas atmosphere at ordinary pressure after the phenol, glyoxal and the basic substance are charged into a reactor.
Inventors:
Takao Maki
Ryogo Araki
Kentaka Moriyasu
Naoko Yamagata
Ryogo Araki
Kentaka Moriyasu
Naoko Yamagata
Application Number:
JP34672491A
Publication Date:
June 18, 2001
Filing Date:
December 27, 1991
Export Citation:
Assignee:
Mitsubishi Chemical Corporation
International Classes:
B01J27/232; B01J31/02; C07B61/00; C07C45/69; C07C49/82; C07C49/84; (IPC1-7): C07C49/82; B01J27/232; B01J31/02; C07C45/69; C07C49/84
Domestic Patent References:
| JP5178783A |
Attorney, Agent or Firm:
Hidetake Komatsu (2 outside)