PURPOSE: To directly obtain the titled substance in high yield and stereo- selectivity, by reacting an olefin compound with a carbamic acid ester in the presence of a Lewis acid using an organic tellurinyl compound as a mediator.
CONSTITUTION: The titled substance can be produced by reacting an olefin compound with a carbamic acid ester in the presence of Lewis acid (preferably a boron trifluoride complex) using an organic tellurinyl compound as a mediator and cyclizing the addition product under mild heating (at ≥70°C). The reaction is preferably carried out by using chlorinated hydrocarbons as a solvent. The titled substance is useful as an intermediate for pharmaceuticals and a raw material for polymers having hydrophilic nature, polarity and specific adsorption capability.
OTSUBO TETSUO
ASO YOSHIO
KO NANSEI
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