Title:
PRODUCTION OF 3-AMINO-2-OXO-PYRROLIDINE, NEW INTERMEDIATE AND ITS USE
Document Type and Number:
Japanese Patent JPH11349567
Kind Code:
A
Abstract:
To obtain the subject compound in high yield by cyclization of a specific compound having a halogen or sulfonic ester group.
This compound of formula II is obtained by cyclization of a compound of formula I [R1 is H, a (substituted) 1-8C alkyl, p-cyanophenyl, p-carbamoyl or the like; R2 is H, a (substituted) 2-8C alkenyl or the like; R3 is H, ClCO, formyl, benzyloxycarbonyl or the like; X is a halogen or sulfonic ester group] pref. using a base (e.g. sodium hydroxide) at -20 to 100°C. By the way, the compound of formula I is prepared by reaction of a compound of formula III pref. in a solvent such as toluene or methyl-isobutyl ketone in the presence of a base (e.g. mesyl chloride).
Inventors:
DRAUZ KARLHEINZ
KNAUP GUENTER
SCHWARM MICHAEL
KNAUP GUENTER
SCHWARM MICHAEL
Application Number:
JP13876399A
Publication Date:
December 21, 1999
Filing Date:
May 19, 1999
Export Citation:
Assignee:
DEGUSSA
International Classes:
C07C229/22; C07C237/06; C07C237/08; C07C237/22; C07C255/60; C07C271/22; C07C305/08; C07C309/70; C07D207/273; C07D207/26; (IPC1-7): C07D207/273; C07C237/06; C07C237/08; C07C271/22; C07C305/08; C07C309/70
Domestic Patent References:
| JPH08508732A | 1996-09-17 | |||
| JPS6383082A | 1988-04-13 |
Attorney, Agent or Firm:
Toshio Yano (3 outside)
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