Title:
PRODUCTION OF BENZAMIDOXIME COMPOUND
Document Type and Number:
Japanese Patent JP3787821
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To obtain a benzamidoxime compound useful as an intermediate important as an agricultural and horticultural fungicide industrially and extremely advantageously.
SOLUTION: A compound of formula I (X1 and X5 each a 1-6C alkyl, a halogen, etc.; X2, X3 and X4 are each H, a 1-6C alkyl, a halogen, etc.) is O- cyclopropy1methylated with cyclopropylmethyl iodide in an inert solvent such as DMF or DMA in the presence of a base (e.g. a carbonate such as Na2CO3 or an organic base such as pyridine) to produce a benzamidoxime compound of formula II. The reaction is carried out at -15°C to the boiling point of the solvent for 10 minutes to tens of hours. A catalyst such as 18-crown 6 may be used depending upon the solvent system or the base used. After the reaction, an aftertreatment is carried out by an ordinary synthetic chemical procedure to give the objective compound of formula II.
Inventors:
Takashi Okabe
Suzuki Tachimi
Hatano Masami
Suzuki Tachimi
Hatano Masami
Application Number:
JP9044596A
Publication Date:
June 21, 2006
Filing Date:
March 19, 1996
Export Citation:
Assignee:
Nippon Soda Co., Ltd.
International Classes:
C07C259/18; (IPC1-7): C07C259/18
Domestic Patent References:
| JP9235262A | ||||
| JP26453A |
Foreign References:
| WO1996019442A1 |
Attorney, Agent or Firm:
Yasunori Matsuhashi