PRODUCTION OF CEPHALOSPORIN DERIVATIVE

Title:

PRODUCTION OF CEPHALOSPORIN DERIVATIVE

Document Type and Number:

Japanese Patent JPS51138694

Kind Code:

A

Abstract:

Cephalosporins of formula (I) and their salts are new (where R is H or OH; Y is NH2, OH or OR4, where R4 is lower alkanoyl, lower alkoxycarbonyl or benzoyl; X is O, S. NH or NMe; Z is H, lower alkyl, benzhydrylphenyl, indan-5-yl, R'OCOCH2 (R' = lower alkyl), R'OOCOCH(Me) or phthalidyl; R1 is CH2oCH2COOH, CH2OCH2COOR', CH2OCH2CONR2R3 or CONR2R3; R2 and r3 are H or lower alkyl). Cpds. (I) are antibacterials active against Gram-positive and -negative bacteria.

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Inventors:

CHIYAARUSU ANDORIYUU REIMONDO
BURAHAMU SHIYURUUTO

Application Number:

JP3347276A

Publication Date:

November 30, 1976

Filing Date:

March 26, 1976

Export Citation:

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Assignee:

PFIZER

International Classes:

C07D249/12; C07D271/10; C07D285/12; C07D501/36; (IPC1-7): A61K31/545; C07D501/06; C07D501/36

Domestic Patent References:

JPS4712579A
JPS4742791A
JPS4949984A	1974-05-15
JPS49101395A	1974-09-25
JPS5188989A	1976-08-04

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