Title:
PRODUCTION OF GUANIDINE DERIVATIVE, ITS INTERMEDIATE THEREOF AND PRODUCTION THEREOF
Document Type and Number:
Japanese Patent JP3032846
Kind Code:
B2
Abstract:
PURPOSE: To provide compounds useful as an intermediate for synthesis of an insecticide and a mitecide.
CONSTITUTION: Compounds of formula I(R is hydrocarbon or acyl; X is electron- attracting group; Y1 and Y2 are ○ or S; A is divalent hydrocarbon), e.g. S- methyl-N-nitro-N-phthaloylisothiourea. The compounds of formula I can be obtained by reacting a compound of formula II with a compound of formula III (Z1 and Z2 are halogen, or Z1 and Z2 together form ○) preferably in the presence of a base (e.g. potassium hydroxide) in a solvent (e.g. acetonitrile) at -50-200°C. The compounds of formula I can be converted into the corresponding quanidine derivatives by reaction with an amine, followed by reaction with a compound of formula R3-NH(CH2)n-B (B is homocycle or heterocycle which may be substituted; (n) is 0 or 1; R3 is H or hydrocarbon).
Inventors:
Kando Yasuyuki
Sho Woman Hideki
Isao Minamida
Sho Woman Hideki
Isao Minamida
Application Number:
JP14429591A
Publication Date:
April 17, 2000
Filing Date:
April 02, 1991
Export Citation:
Assignee:
Takeda GmbH
International Classes:
A01N47/28; C07C279/04; C07C279/18; C07C335/38; C07C335/40; C07C335/42; C07D207/408; C07D209/48; C07D213/36; C07D213/61; C07D239/26; C07D277/20; C07D277/28; C07D277/32; C07D307/66; C07D333/36; C07F9/572; (IPC1-7): C07D207/408; C07D209/48
Domestic Patent References:
| JP3157308A |
Other References:
Ｊ．Ｏｒｇ．Ｃｈｅｍ．，Ｖｏｌ．４３，Ｎｏ．１８，ｐ．３５５３−３５５９（１９７８）
Attorney, Agent or Firm:
Shuichi Takahashi (2 outside)