PURPOSE: To obtain the subject highly purified compound useful as an intermediate of an agricultural chemical or a modicine in high yield by washing the subject crude compound with an aqueous solution of dehalogenating hydrogen reagent and distilling under reduced pressure in a nitrogen atmosphere in the presence of an antioxidant.
CONSTITUTION: 5,6,7,8-tetrahydronaphthol is reacted with carbon dithiochloride in the presence of a dehalogenating hydrogen reagent (e.g. alkali metal hydroxide) and resultant crude 0-2-(5,6,7,8-tetrahydronaphthoxy)-chlorothioformate is washed with an aqueous solution of dehalogenating hydrogen reagent having 1-10 N, preferably 2-5N concentration, and added to said compound in an amount of 0.1-20wt.%, preferably 5-10wt.% mixture is distilled under ≤2.0mmHg, preferably ≤1.0mmHg pressure at a temperature of 100-170°C, preferably 100-150°C in a nitrogen atmosphere.
AWANO YUTAKA
TSUZUKI KENJI
