Title:
イソプレノイドの生成
Document Type and Number:
Japanese Patent JP5074185
Kind Code:
B2
Abstract:
The present invention relates to a process for the production of isoprenoids Coenzyme Q-10 by microorganisms. More particularly, the present invention relates to a process for increased production of Coenzyme Q-10 by microorganisms of the genus Rhodobacter, preferably of the species R. sphaeroides which have been transformed with one or more gene(s) of the mevalonate (mev) operon from a different microorganism, preferably of the genus Paracoccus, more preferably of the species P. zeaxanthinifaciens, whereby the mev operon is mutated leading to an increased coenzyme Q-10 production. Sequences carrying such a mutation as well as a microorganism carrying such a mutated mev operon are also included.
Inventors:
Berry, alan
Manhart, christian
Simic, Petra
Manhart, christian
Simic, Petra
Application Number:
JP2007526356A
Publication Date:
November 14, 2012
Filing Date:
August 11, 2005
Export Citation:
Assignee:
DSM IP ASSETS B.V.
International Classes:
C12N1/21; C12N15/09; C12P7/66; C12P23/00
Foreign References:
| WO2002099095A1 |
Attorney, Agent or Firm:
Yuichi Yamada
Masakazu Noda
Yoshinori Shimizu
Masakazu Noda
Yoshinori Shimizu