To provide a new method for production with which a foreign enzyme protein is produced by a transgenic silkworm.
The high-molecular weight foreign enzyme protein can easily be obtained in a large amount from a silk gland or a silk thread of the transgenic silkworm as follows. The transgenic silkworm is prepared by transferring a gene group containing a first gene containing a gene of GAL4 or an analog thereof linked to the downstream side of a promoter for inducing the expression specifically in the silk gland and a second gene containing a gene of a protein expressed specifically in the silk gland and linked to the downstream side of a gene of a UAS (an upstream activating sequence) and a gene of the foreign enzyme protein linked to the downstream side of the gene of the protein expressed specifically in the silk gland into the chromosome.
COPYRIGHT: (C)2007,JPO&INPIT
Kenya Ohashi
Kiyokawa Iwao
Toshiki Tamura
Isao Kobayashi
Uchino Keiro
NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
| JP2005095063A | ||||
| JP2003325188A |
| WO2004101748A1 |
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