Title:
PRODUCTION OF MODIFIED PROTEIN AND FOULING REMOVING AGENT FOR CONTACT LENS
Document Type and Number:
Japanese Patent JP3825502
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To produce a modified protein, capable of maintaining enzymic activities high even in a state of an aqueous solution, stably preservable and useful as a fouling removing agent, etc., for contact lenses by reacting a specific phosphorylcholine group-containing compound with a protein.
SOLUTION: A phosphorylcholine group-containing compound represented by formula I [R1 is a functional group bondable to a functional group in a protein; X1 is a bivalent organic residue without containing phosphorylcholine; X is an organic residue of a compound containing the phosphorylcholine group such as 2-methacryloyloxyethylphosphorylcholine; (a) is O or 1] is reacted with a protein such as a hydrolase (e.g. a protease) to thereby provide the objective modified protein, represented by formula II [Pro is a residue of the protein; R is a bivalent organic residue derived from the functional group bondable to the functional group in the protein; (b) is a positive number of ≥1] and useful as an active component, etc., of a fouling removing agent for contact lenses.
Inventors:
Sakaki Shujiro
Kenshiro Suto
Kazuo Matsuyama
Yasumi Koinuma
Nobuo Nakabayashi
Kazuhiko Ishihara
Kenshiro Suto
Kazuo Matsuyama
Yasumi Koinuma
Nobuo Nakabayashi
Kazuhiko Ishihara
Application Number:
JP14922996A
Publication Date:
September 27, 2006
Filing Date:
June 11, 1996
Export Citation:
Assignee:
Nippon Oil & Fat Co., Ltd.
Nobuo Nakabayashi
Kazuhiko Ishihara
Japan Science and Technology Agency
Nobuo Nakabayashi
Kazuhiko Ishihara
Japan Science and Technology Agency
International Classes:
C12N9/14; G02C13/00; C11D3/386; C11D7/42; (IPC1-7): C12N9/14; C11D3/386; C11D7/42; G02C13/00
Domestic Patent References:
| JP9051793A | ||||
| JP6041156A | ||||
| JP6157269A |
Attorney, Agent or Firm:
Hajime Sakai