PRODUCTION OF N-ACYL DERIVATIVE AND DERIVATIVE OF THE SAME KIND

Title:

PRODUCTION OF N-ACYL DERIVATIVE AND DERIVATIVE OF THE SAME KIND

Document Type and Number:

Japanese Patent JP2001072652

Kind Code:

A

Abstract:

To produce the subject compound in high yield by reacting a carboxamide with a glyoxal monoacetal derivative in the presence of a carboxylic acid.

(A) A carboxamide represented by the formula: R1-CONH2 [R1 is H, a 1-12C alkyl or a (substituted) aryl] is reacted with (B) a glyoxal monoacetal derivative represented by formula I [R2 is H, a 1-12C alkyl or a (substituted) aryl; R3 is a 1-12C alkyl] in the presence of (C) a carboxylic acid represented by the formula; R4-COOH (R4 is a 1-12C alkyl), preferably at 40-200°C under 200-1,000 mbars to thereby produce a compound represented by formula II [X is CH(OR3)2 or COOR3]. In the above reaction, the components A and C are used in respective amounts of 250-800 mol% based on the component B. The ratio of the components A:C is preferably 1:1 expressed in terms of molar ratio.

Inventors:

PAUST JOACHIM
ERNST HANSGEORG
KACZMAREK REINHARD
HAGEN IEEDIKKE

Application Number:

JP2000252489A

Publication Date:

March 21, 2001

Filing Date:

August 23, 2000

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Assignee:

BASF AG

International Classes:

C07B61/00; C07C231/08; C07C233/18; C07C233/47; C07C233/69; C07C233/83; (IPC1-7): C07C231/08; C07C233/18

Attorney, Agent or Firm:

Toshio Yano (4 outside)

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