Title:
PRODUCTION OF NITRILES
Document Type and Number:
Japanese Patent JPH0597714
Kind Code:
A
Abstract:
PURPOSE: To produce nitriles from aldehydoximes under nearly neutral and mild conditions in high efficiency by using a haloiminium salt as a dehydration agent.
CONSTITUTION: A nitrile (e.g. 3-nitrobenzonitrile) is produced by using a compound of formula (R1 and R2 are lower alkyl; X is halogen; (n) is 2 or 3), e.g. 2-chloro-1,3-dimethylimidazolinium chloride or 2-chloro-1,3-dimethyl-3,4,5,6- tetrahydropyrimidium chloride as a dehydration agent, adding about 1mol of the compound of formula and about 2mol of a base (e.g. pyridine or triethylamine) to 1mol of an aldehydoxime compound (e.g. 3- nitrobenzaldehydoxime) and making the components to react with each other at room temperature or thereabout.
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Inventors:
ISOBE TOSHIO
SAITO MASAAKI
SAITO MASAAKI
Application Number:
JP25549091A
Publication Date:
April 20, 1993
Filing Date:
October 02, 1991
Export Citation:
Assignee:
SHIRATORI PHARM
International Classes:
C07D233/32; C07B43/08; C07C253/00; C07C255/03; C07C255/32; C07C255/50; C07C255/54; (IPC1-7): C07B43/08; C07C253/00; C07C255/03; C07C255/32; C07C255/50; C07C255/54; C07D233/32
Attorney, Agent or Firm:
Miyuki Ariga (2 outside)
Next Patent: JPS597715