Title:
PRODUCTION OF PYRAZOLONES
Document Type and Number:
Japanese Patent JP3719736
Kind Code:
B2
Abstract:
PURPOSE: To easily obtain a pyrazolone derivative useful as an intermediate raw material for agrochemicals, pharmaceuticals and other synthetic chemicals at a low cost by reacting a dihalocarboxylic acid derivative or a haloacrylic acid derivative with a hydrazine derivative.
CONSTITUTION: This pyrazolone derivative of formula III is produced by reacting (A) a 2,3-dihalocarboxylic acid derivative of formula I [R1 and R2 are each H, an alkyl or phenyl; X is a halogen; Z is OR3 (R3 is a lower alkyl) or NR4R5 (R4 and R5 are each H or an alkyl)] or (B) a 2-haloacrylic acid derivative of formula II with (C) a hydrazine derivative of formula, R-HNNH2 (R is H, an alkyl, allyl, an aryl or an aralkyl). The component A is preferably a 2,3- dichlorocarboxylic acid ester or 2,3-dichlorocarboxylic acid amide and the component B is preferably a 2-chloroacrylic acid ester or 2-chloroacrylic acid amide.
Inventors:
Yasuo Yamamoto
Naoki Shirakawa
Shinichi Takano
Yoshio Kawai
Naoki Shirakawa
Shinichi Takano
Yoshio Kawai
Application Number:
JP10763295A
Publication Date:
November 24, 2005
Filing Date:
May 01, 1995
Export Citation:
Assignee:
Japan Hydrazine Industry Co., Ltd.
International Classes:
C07D231/20; C07D231/22; (IPC1-7): C07D231/20; C07D231/22
Other References:
C David Gutsche and Manny Hillman,Reactions of Ethyl Diazoacetate with Aromatic Compounds Containing Hetero Atoms Attached to teh Benz,Journal of American Chemical Society,米国,1954年,Vol.76,2236-2240
Bruce J. Gaede and Lisa L. McDermott,Novel Perfluoroalkyl-substituted Pyrazoles.1.Hydroxypyrazoles,J. Heterocyclic Chem.,1993年,Vol.30,No.49(1993),pages49-54
Bruce J. Gaede and Lisa L. McDermott,Novel Perfluoroalkyl-substituted Pyrazoles.1.Hydroxypyrazoles,J. Heterocyclic Chem.,1993年,Vol.30,No.49(1993),pages49-54
Attorney, Agent or Firm:
Naozumi Ono
Sachiko Okunuki
Sachiko Okunuki