Title:
PRODUCTION OF RUTHENIUM-IODO-OPTICALLY ACTIVE PHOSPHINE COMPLEX AND PRODUCTION OF OPTICALLY ACTIVE 4-METHYL-2-OXETANONE USING THE SAME COMPLEX
Document Type and Number:
Japanese Patent JP3437623
Kind Code:
B2
Abstract:
PURPOSE: To obtain a ruthenium-iodo-optically active phosphine complex having high catalytic activity and useful for catalysts, etc., for producing an optically active 4-methyl-2-oxetanone which is an intermediate for polymers, medicines, liquid crystal, etc., by reacting a specific ruthenium-optically active phosphine complex with an inorganic iodide.
CONSTITUTION: A ruthenium-optically active phosphine complex expressed by formula I [Et is ethyl; CBP is formula II (R1 is aryl or a 3-8C cycloalkyl) or formula III (R2 is aryl or a 3-8C cycloalkyl; R3 is methyl or methoxy; R4 is H, methyl, methoxy or a di-lower-alkyl-substituted amino; R3 and R4 form tetrahydronaphthyl together with adjacent phenyl group)] is reacted with an inorganic iodide (e.g. potassium iodide) to provide the objective complex having a high catalytic activity and capable of providing an optically active 4-methyl-2- oxetanone which is a polymer raw material, a raw materials for synthesizing medicines or an intermediate for liquid crystal materials, etc., as a catalyst for asymmetric synthesis providing a product having high optical purity.
Inventors:
Yoshiki Okeda
Yoshiharu Gonda
Yoji Hori
Akio Yamaguchi
Toshimitsu Hagiwara
Yoshiharu Gonda
Yoji Hori
Akio Yamaguchi
Toshimitsu Hagiwara
Application Number:
JP1311594A
Publication Date:
August 18, 2003
Filing Date:
January 12, 1994
Export Citation:
Assignee:
Takasago International Corporation
International Classes:
C07D305/12; B01J31/24; C07B61/00; C07F9/50; C07F15/00; (IPC1-7): C07F9/50; B01J31/24; C07D305/12
Domestic Patent References:
| JP5255142A |
Attorney, Agent or Firm:
Nobuo Ono