Title:
PRODUCTION OF TAURINE ANALOG
Document Type and Number:
Japanese Patent JP3874820
Kind Code:
B2
Abstract:
PURPOSE: To economically obtain a taurine analog such as hypotaurine in high yield and high purity by alkali-treating a sulfonate of styrene/divinylbenzene copolymer of a new amino/guanidinoethyl disulfoxide.
CONSTITUTION: A sulfonate of a styrene/divinylbenzene copolymer of amino/ guanidinoethyl disulfoxide of formula I [RP is a styrene/divinylbenzene copolymer; R) is H or C(NH)NH2; R2 is H or COOH] is contacted with an alkali (preferably an alkali metal hydroxide or ammonia), decomposed and generated amino/guanidinosulfinic acid of formula II such as hypotaurine is selectively eluted. The sulfonate of the formula is obtained by, e.g. obtaining cystamine disulfoxide/dihydrochloride by oxidizing cysteamine hydrochloride with H2O2 by using KI as a catalyst, and reacting with a strongly acidic cation-exchange resin.
More Like This:
Inventors:
Tomoko Osumi
Katsumata Manabu
Tomoyasu Tashiro
Kasaburo Uchiku
Katsumata Manabu
Tomoyasu Tashiro
Kasaburo Uchiku
Application Number:
JP11893895A
Publication Date:
January 31, 2007
Filing Date:
April 21, 1995
Export Citation:
Assignee:
Mutual medicine Co., Ltd.
International Classes:
C07C313/04; C07C315/00; C07C313/02; C07C317/28; C07C317/44; C07C381/04; (IPC1-7): C07C317/28; C07C315/00; C07C317/44; C07C381/04
Domestic Patent References:
| JP62138426A | ||||
| JP62081365A |
Attorney, Agent or Firm:
Toda parent man