Title:
プロポフォール含有水中油型エマルション組成物及びその製造方法
Document Type and Number:
Japanese Patent JP6392883
Kind Code:
B2
Abstract:
Provided are a propofol-containing oil-in-water emulsion composition having high stability even in a case in which the emulsion composition is charged into a plastic container; and a method for producing the same. Provided is a propofol-containing oil-in-water emulsion composition including at least one selected from the group consisting of trishydroxymethylaminomethane, phosphoric acid, and triethanolamine; propofol; an oily component; an emulsifier; and water, in which a dissolved oxygen concentration is 5 mg/L or less and an average emulsion particle size is 180 nm or less.
Inventors:
Yoshinori Sakata
Yasuyuki Izumi
Shigecho Tsujihata
Yasuyuki Izumi
Shigecho Tsujihata
Application Number:
JP2016550346A
Publication Date:
September 19, 2018
Filing Date:
September 24, 2015
Export Citation:
Assignee:
FUJIFILM Corporation
International Classes:
A61K31/05; A61K9/107; A61K47/12; A61K47/18; A61K47/20; A61K47/22; A61P23/00
Domestic Patent References:
| JP2004526730A | ||||
| JP2012210315A | ||||
| JP2006504771A | ||||
| JP2010534555A |
Foreign References:
| CN102805728A | ||||
| US6177477 | ||||
| WO2006112276A1 |
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes