プロスタグランジン誘導体 - Taisho Pharmaceutical Co., Ltd.

Title:

プロスタグランジン誘導体

Document Type and Number:

Japanese Patent JP4354644

Kind Code:

B2

Abstract:

A sleep-inducing preparation which comprises as an effective ingredient a prostaglandin derivative represented by the formula: wherein X is a halogen atom, Y is a group represented by (CH2)m, a cis-vinylene group or a phenylene group, Z is an ethylene group, a trans-vinylene group, OCH2 or S(O)nCH2, R<1> is a C3-10 cycloalkyl group, a C3-10 cycloalkyl group substituted with C1-4 alkyl group(s), a C4-13 cycloalkylalkyl group, a C5-10 alkyl group, a C5-10 alkenyl group, a C5-10 alkynyl group or a bridged cyclic hydrocarbon group, R<2> is a hydrogen atom, a C1-10 alkyl group or a C3-10 cycloalkyl group, m is an integer of 1 to 3, and n is 0, 1 or 2, a pharmaceutically acceptable salt thereof or a hydrate thereof.

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Inventors:

Fumie Sato
Toru Tanami
Kazuya Kameo
Kenji Yamada
Okuyama Shigeru
Naoya Ono

Application Number:

JP2000550825A

Publication Date:

October 28, 2009

Filing Date:

May 25, 1999

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