Title:
改変プロペプチド領域を備えるプロテアーゼ
Document Type and Number:
Japanese Patent JP7134629
Kind Code:
B2
Abstract:
The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. Bacillus sp. host cells). The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
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Inventors:
Babe, lilia maria
Fioresi, Carol Marie
Fudeheville, Fritz
Mulder, Harm
Fioresi, Carol Marie
Fudeheville, Fritz
Mulder, Harm
Application Number:
JP2017565842A
Publication Date:
September 12, 2022
Filing Date:
June 17, 2016
Export Citation:
Assignee:
Danisco US Inc.
International Classes:
C12N15/57; C12N1/21; C12N9/56; C12N15/75
Domestic Patent References:
| JP2005512567A | ||||
| JP2012524542A |
Other References:
J.Microbiol.Biotechnol.,2014年,Vol.24,No.2,pp.197-208
Attorney, Agent or Firm:
Yamazaki Yuzo
Toshiaki Akamatsu
Tadao Naito
Toshiaki Akamatsu
Tadao Naito
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