PROTEIN BINDING TO MEDICINE - SMITHKLINE BEECHAM CORP

Title:

PROTEIN BINDING TO MEDICINE

Document Type and Number:

Japanese Patent JPH11196873

Kind Code:

A

Abstract:

To obtain an isolated polynucleotide encoding a polypeptide having a specific amino acid sequence and useful for expressing the protein (CSBP β) capable of binding to a cytokine suppressive anti-inflammatory drug (CSAID).

This isolated polynucleotide is selected from a polynucleotide having at least 75% identity with a polypeptide having an amino acid sequence of the formula, a polynucleotide encoding the same amino acid sequence by the multiplicity of genetic codes, a polynucleotide complementary to the above polynucleotides, and a polynucleotide containing at least the 15 continuous bases of the above three polynucleotides. The isolated polynucleotide is obtained by a standard cloning and screening method such as a cDNA-cloning method based on an mRNA from spermary and T-cells.

Inventors:

PETER COLON MCDONNELL
YOUNG PETER RONALD

Application Number:

JP36975797A

Publication Date:

July 27, 1999

Filing Date:

December 09, 1997

Export Citation:

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Assignee:

SMITHKLINE BEECHAM CORP

International Classes:

A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P29/00; A61P43/00; C07K14/47; C07K14/705; C07K16/18; C12N1/21; C12N15/09; C12N15/12; C12P21/02; C12P21/08; C12Q1/02; C12Q1/48; C12Q1/68; A01K67/027; C12R1/19; (IPC1-7): C12N15/09; A01K67/027; A61K38/00; A61K39/395; A61K45/00; A61K48/00; C07K14/47; C07K16/18; C12N1/21; C12P21/02; C12Q1/02; C12Q1/48; C12Q1/68

Attorney, Agent or Firm:

Aoyama Ryo (1 person outside)

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